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  • Title: [Effect of vagotomy on glycogen content, succinate dehydrogenase, cytochrome-c-oxidase and lactate dehydrogenase activities in myocardium in experimental aortostenosis].
    Author: Zelenina NM.
    Journal: Ukr Biokhim Zh (1978); 1980; 52(1):84-7. PubMed ID: 6246664.
    Abstract:
    The glycogen contents, succinate dehydrogenase, cytochrome-c-oxidase and lactate dehydrogenase activities in tissues of cardiac left cavity of vagotomized and nonvagotomized rabbits were studied two days and two weeks after aortostenosis and false operation. It is established that in vagotimized rabbits the prolongation of the hyperfunction period causes a less pronounced decrease in the glycogen level and a higher level of the succinate dehydrogenase and cytochrome-c-oxidase activities. A conclusion is drawn that heart hyperfunction under conditions of vagotomy is accompanied by a less pronounced inhibition of aerobic and insignificant intensification of anaerobic oxidation processes as compared to their changes in rabbits with the heart maintained innervation.
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