These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Novel analogues of enkephalin: indentification of functional groups required for biological activity.
    Author: Gorin FA, Balasubramanian TM, Cicero TJ, Schwietzer J, Marshall GR.
    Journal: J Med Chem; 1980 Oct; 23(10):1113-22. PubMed ID: 6252322.
    Abstract:
    Novel tri- and tetrapeptide analogues of enkephalin, in conjunction with earlier structure-activity data, confirm that chemical substitutents present in the first and fourth residues of enkephalin are required for in vitro biological activity. A class of arylamino and alkylamino derivatized tripeptides also were found to have significant in vitro opioid-like activity indistinguishable from [D-Ala2,D-Leu5]enkephalin and morphine.
    [Abstract] [Full Text] [Related] [New Search]