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  • Title: The uterotrophic effect of delta 9 THC in ovariectomized rats and mice.
    Author: Solomon J, Schoenfeld D.
    Journal: Res Commun Chem Pathol Pharmacol; 1980 Sep; 29(3):603-11. PubMed ID: 6252582.
    Abstract:
    We have reanalyzed the statistics on uterine weights used by Virgo in his article, The Estrogenicity of Delta-9-Tetrahydrocannabinol (THC): THC Neither Blocks nor Induces Ovum Implantation, nor does it Effect Uterine Growth, which appeared in Res. Comm. Chem. Path. and Pharmacol. 25:65-77 (1979). The reanalysis shows that administration of 3 and 6 mg/kg delta 9 THC to ovariectomized mice results in highly significant (P < .002; P < .0001 respectively) increases in uterine weights. These data are in accord with the uterotrophic effect of delta 9 THC observed in ovariectomized rats.
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