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  • Title: Serial cytogenetic studies of nonendemic Burkitt's lymphoma cell lines.
    Author: Douglass EC, Magrath IT, Lee EC, Whang-Peng J.
    Journal: J Natl Cancer Inst; 1980 Nov; 65(5):891-5. PubMed ID: 6253706.
    Abstract:
    Cytogenetic study of nonendemic Burkitt's lymphoma (BL) cell lines showed a translocation of chromosomes #8 and #14, t(8;14), present in 16 of the 18 lines examined. Serial cytogenetic studies of nine of these lines showed the t(8;14) to be stable and present in all cells examined. Although many other chromosome aberrations were present, they did not demonstrate the stability or the pervasiveness of the t(8;14). The significance of these results and previously reported cytogenetic studies on the etiology of BL was discussed.
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