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  • Title: Hypothalamo-pituitary-adrenal axis in patients with prostatic carcinoma.
    Author: Madajewicz S, Bhargava A, Wajsman Z, Mittelman A, Fitzpatrick J, Murphy GP.
    Journal: Oncology; 1980; 37(6):373-5. PubMed ID: 6253857.
    Abstract:
    Insulin-induced pituitary growth hormone (GH), adrenocorticotrophic hormone (ACTH) and adrenal cortical response were studied in 12 patients with prostatic carcinoma. 3 patients demonstrated significant abnormal GH release associated with concentrations which remained on a high plateau during the study. 5 patients showed lack of ACTH-cortisol response to insulin-induced hypoglycemia. Those patients subsequently presented clinically with rapidly progressing disease.
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