These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
Pubmed for Handhelds
PUBMED FOR HANDHELDS
Search MEDLINE/PubMed
Title: Involvement of DNA gyrase in the transcription of ribosomal RNA. Author: Oostra BA, Gruber M. Journal: Nucleic Acids Res; 1980 Sep 25; 8(18):4235-46. PubMed ID: 6253912. Abstract: The DNA gyrase inhibitor novobiocin specifically inhibits the transcription of ribosomal RNA in vivo while protein synthesis and the mRNA transcription are only partly affected. In vitro the novobiocin inhibition is only observed when protein fraction, which stimulates ribosomal RNA synthesis, is present. These results indicate that DNA gyrase is involved in the transcription of ribosomal RNA, probably at an initiation step.[Abstract] [Full Text] [Related] [New Search]