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  • Title: [Hormonal regulation of heparin clearance in immobilization stress in rats].
    Author: Kudriashov BA, Shapiro FB, Ul'ianov AM.
    Journal: Probl Endokrinol (Mosk); 1980; 26(5):59-63. PubMed ID: 6253985.
    Abstract:
    Intensity of heparin (H) clearance is reduced and the latter gets retained in the blood flow in rats subjected to immobilization stress. A stable fall is seen when immobilization is continued not less than 20 minutes. A decrease in the rate of H secretion from the blood flow is associated with ACTH concentration in the blood. Immobilization stress does not affect the intensity of H clearance in the animals with ACTH-release blocked by DOCA administration. ACTH use was conducive to a further decrease in H clearance intensity in animals exposed to immobilization. The rate of H secretion from the blood flow in this case is minimum and significantly differs from the rate of H clearance in animals immobilized without ACTH administration.
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