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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Evidence for homologous actions of pro-opiocortin products.
    Author: Walker JM, Akil H, Watson SJ.
    Journal: Science; 1980 Dec 12; 210(4475):1247-9. PubMed ID: 6254152.
    Abstract:
    alpha-Melanocyte-stimulating hormone (alpha-MSH), a modified fragment of adrenocorticotropic hormone, derives from the same biosynthetic route as beta-endorphin and is stored by the same arcuate neurons. Microinjection of alpha-melanocyte-stimulating hormone and several related peptides into the periaqueductal gray matter significantly reduced responsiveness to pain and had a behavioral profile similar to that produced by beta-endorphin.
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