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  • Title: Glioblastoma multiforme with tuberous sclerosis. Report of a case.
    Author: Padmalatha C, Harruff RC, Ganick D, Hafez GB.
    Journal: Arch Pathol Lab Med; 1980 Dec; 104(12):649-50. PubMed ID: 6254467.
    Abstract:
    Gliomas of the CNS associated with tuberous sclerosis have been well documented; malignant degeneration to glioblastoma multiforme, however, is rare. We studied a 17-year-old boy with stigmata of tuberous sclerosis and a cerebral glioblastoma multiforme. The rarity of this occurrence suggests that neoplasms arising from hamartomas may behave differently than those CNS tumors that arise apparently de novo.
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