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  • Title: Immune profile of infectious bursal disease: I. Effect of infectious bursal disease virus on peripheral blood T and B lymphocytes of chickens.
    Author: Sivanandan V, Maheswaran SK.
    Journal: Avian Dis; 1980; 24(3):715-25. PubMed ID: 6255926.
    Abstract:
    A comparison was made of absolute numbers of peripheral blood B and T lymphocytes, as defined by the anti-bursal and anti-thymus sera, in chickens infected with infectious bursal disease virus at one day and 3 weeks of age by age-matched controls. Birds were evaluated sequentially at weekly intervals for a period of 8 weeks postinfection. The severity of depressions of B-lymphocyte numbers was found to be age-dependent: the birds infected at one day of age showed a more severe depletion than those infected at 3 weeks of age. The T-lymphocyte numbers were less markedly affected in infected chickens of either age group.
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