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  • Title: Effect of prostacyclin on platelet-activating factor induced rabbit and platelet aggregation.
    Author: Bussolino F, Camussi G.
    Journal: Prostaglandins; 1980 Nov; 20(5):781-91. PubMed ID: 6258196.
    Abstract:
    In this paper, the effect of prostacyclin (PGI2) on the aggregation induced by Platelet-activating factor (PAF), a phospholipid mediator of anaphylaxis, was studied. Synthetic PGI2 and PGI2-like activity generated from rabbit aorta were demonstrated to be effective inhibitors of PAF-induced rabbit platelet aggregation and release of 3H-serotonin (3H-5HT).
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