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  • Title: [One hundred and twenty-three cases of sickle-cell trait (author's transl)].
    Author: Piéron R, Mafart Y, Lesobre B, Meyniel D, Varsat B.
    Journal: Sem Hop; ; 57(1-2):16-21. PubMed ID: 6258231.
    Abstract:
    One hundred and twenty-three cases of sickle-cell trait (122 negro immigrants) are studied in a department of internal medicine. The frequencies of G6PD deficiency, anemia, splenomegaly and tuberculosis are neighbouring at the negro without hemoglobinopathy. The relationship between the sickle-cell trait and the reason of admission of the final diagnosis il likely in 2,4 % of the cases, doubtfully in 15,4 %, null in the other cases. The occasional (hemolytic, thrombotic, painful, visceral, osseous) manifestations of the sickle-cell trait (apart from the constant hyposthenuria) and their mechanism are summarized and discussed.
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