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  • Title: The effect of physostigmine on (Na+ + K+)-ATPase activity in different rat brain regions.
    Author: Stojanović T, Djuricić BM, Mrsulja BB.
    Journal: Experientia; 1980 Dec 15; 36(12):1348-50. PubMed ID: 6258966.
    Abstract:
    The activity of (Na+ + K+)-ATPase and acetylcholine esterase were followed in rat brain cerebral cortex, caudate, thalamus, hippocampus and medulla after i.v. administration of physostigmine. Both enzymes were found to be inhibited in a dose-dependent manner. The most pronounced inhibition of (Na+ + K+)-ATPase was found in caudate, where the highest activity of acetylcholine esterase is found.
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