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  • Title: [3':5'-AMP-dependent phosphorylation of muscular membrane proteins and calcium transport].
    Author: Kurskiĭ MD, Kondratiuk TP.
    Journal: Ukr Biokhim Zh (1978); 1980; 52(4):525-38. PubMed ID: 6259790.
    Abstract:
    The data are presented concerning the role of cAMP-dependent phosphorylation of sarcoplasmic reticulum and sarcolemma proteins in the transport of Ca2+ through the cardiac skeletal and smooth muscle membranes. Phosphorylation of membrane proteins by soluble and membrane-bound cAMP-dependent protein kinases is shown to have a regulating effect on Mn2+-, Ca2+-ATPase activity and to change membrane permeability for Ca2+. The molecular mechanisms and the character of the interaction between the transport systems and the phosphorylating protein substrates have not been yet established.
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