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Title: Ion pathways in proteins of the sarcoplasmic reticulum. Author: MacLennan DH, Reithmeier RA, Shoshan V, Campbell KP, LeBel D, Herrmann TR, Shamoo AE. Journal: Ann N Y Acad Sci; 1980; 358():138-48. PubMed ID: 6259987. Abstract: In summary, we have begun to characterize three different ion pathways in the sarcoplasmic reticulum. Ca2+-ionophoric activity has been traced to a 13,000-dalton CNBr fragment localized at the amino terminus of the ATPase molecule... The pathway involved in Ca2+ release can be distinguished from the pathway involved in Ca2+ uptake by its insensitivity to quercetin. An anion pathway is sensitive to DIDS and appears to be localized in the ATPase molecule[Abstract] [Full Text] [Related] [New Search]