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  • Title: Selective neurotoxic action of capsaicin on glomerular C-type terminals in rat substantia gelatinosa.
    Author: Palermo NN, Brown HK, Smith DL.
    Journal: Brain Res; 1981 Mar 16; 208(2):506-10. PubMed ID: 6260297.
    Abstract:
    This study demonstrates that capsaicin exerts a selective neurotoxic action to induce degeneration of glomerular C-type nerve terminals in adult rats. Since the C terminals may be essential components of the circuitry for modulation of pain, it is suggested that capsaicin induced analgesia is the result of this neurotoxic action.
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