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  • Title: Hepatic and splenic scintigraphy in idiopathic systemic amyloidosis.
    Author: Rao BK, Padmalatha C, Au Buchon J, Lieberman LM.
    Journal: Eur J Nucl Med; 1981 Apr; 6(4):143-6. PubMed ID: 6260498.
    Abstract:
    Technetium-99m sulfur colloid (SC) and Technetium-99m pyrophosphate (PYP) scintigrams in a patient with idiopathic systemic amyloidosis were abnormal. Hepatic SC distribution was nonhomogeneous. Spleen showed reduced SC uptake and a large focal defect at its upper pole. Splenic localization of PYP was seen on a bone scan. On histologic examination the abnormal scintigraphic sites showed heavy amyloid deposition. Splenic localization of skeletal radiotracer due to amyloidosis has not been previously reported.
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