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  • Title: [Clinical resistance of herpetic keratitis to antiviral agents (author's transl)].
    Author: Colin J, Chastel C, Baikoff G, Renard G.
    Journal: J Fr Ophtalmol; 1981; 4(1):57-60. PubMed ID: 6260850.
    Abstract:
    Clinical resistance of herpetic keratitis to antiviral agents constitutes one of the reasons for failure of treatment after their administration. A retrospective study of 42 cases of superficial herpetic keratitis resistant to IDU, IDU and IDC, and Ara-A demonstrated that in 2 out of 3 cases this resistance appeared in patients previously treated locally with antiviral compounds for anterior ocular lesions. Patients resistant to IDU were then treated with Ara-A, and those not responding to Ara-A, with TFT. Resistance may be observed following this new treatment during the subsequent relapses.
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