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  • Title: [Determination by three technics of cellular immunology of the antigenic determinants of the Ly-Li system expressed on human B lymphocytes].
    Author: Sasportes M, Mawas C, Crosier P, Charmot D, Legrand L, Dausset J.
    Journal: C R Acad Hebd Seances Acad Sci D; 1976 Sep 27; 283(6):663-6. PubMed ID: 62629.
    Abstract:
    A clear correlation has been observed between the presence of the antigenic B cell system Ly-Li detected serologically, and 3 cellular immunology techniques: 1. MLR inhibition by anti-Li serum; 2. level of restimulation of anti-Ly-Li in vitro primed lymphocytes; 3. detection of HLA-D alleles by homozygous typing cells. These results suggest that the allelic products detected serologically may be identical to those detected by the first two techniques, namely MLR inhibition and in vitro primed lymphocyte typing, and possibly HLA-D typing using homozygous typing cells, although the correlation was found to be repeatedly less clear for the last technique.
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