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  • Title: [Meiotic maturation of the ovocyte of Xenopus laevis : a 4-step mechanism].
    Author: Huchon D, Ozon R, Fischer EH, Demaille JG.
    Journal: C R Seances Acad Sci III; 1981 Jan 05; 292(1):65-7. PubMed ID: 6263509.
    Abstract:
    Microinjection of the pure inhibitor (1) of cAMP dependent protein kinases (1.5 muM) into Xenopus oocytes triggered 100% germinal vesicle break down (GVBD), faster than progesterone and slower than the maturation promoting factor (MPF). Cholera toxin does not block (I) induced maturation; however cycloheximide inhibits (I) but not MPF induced GVBD.
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