These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Interaction between cyclic adenosine-3':5'-monophosphate phosphodiesterase and structural analogs of the substrate].
    Author: Kochetkova MN, Guliaev NN, Tunitskaia VL, Severin ES.
    Journal: Biokhimiia; 1981 Feb; 46(2):353-60. PubMed ID: 6264977.
    Abstract:
    The interaction between synthetic structural analogs of cyclic adenosine-3':5'-monophosphate (3':5'-AMP) and rat liver 3':5'-AMP phosphodiesterase was studied. Various groups, including those capable of covalent binding to the protein, were injected into certain sites of the 3':5'-AMP molecule. All the compounds tested exerted an inhibiting effect; in seven cases this effect was irreversible. Some peculiarities of 3':5'-AMP binding in the enzyme active center are discussed.
    [Abstract] [Full Text] [Related] [New Search]