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  • Title: Extrachromosomal rDNA of Tetrahymena thermophila is not a perfect palindrome.
    Author: Kiss GB, Pearlman RE.
    Journal: Gene; 1981 Apr; 13(3):281-7. PubMed ID: 6266918.
    Abstract:
    We have determined the restriction-endonuclease-cleavage map and the nucleotide sequence of the central 1.4 kb fragment of the macronuclear extrachromosomal rDNA of Tetrahymena thermophila. These data demonstrate that this molecule is not a perfect palindrome, having a 29 bp AT-rich non-palindromic sequence at its center. This observation is important in determining the mechanism by which a single chromosomally integrated rRNA gene in the micronucleus is rearranged and amplified during sexual development to yield multiple copies of extrachromosomal rDNA in the macronucleus.
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