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  • Title: Serum prolactin, gonadotrophin and oestrogen levels in women receiving hormone replacement therapy.
    Author: Lind T, Cameron EH, Hunter WM.
    Journal: Br J Obstet Gynaecol; 1978 Feb; 85(2):138-41. PubMed ID: 626723.
    Abstract:
    Prolactin, oestrone, oestradiol, FSH and LH concentrations have been determined in postmenopausal women receiving different forms of hormone replacement therapy. While the serum oestrogen levels achieved were sufficient to cause a significant decrease in circulating FSH and LH levels, no significant change in prolactin concentrations was found. Two other findings are of interest: despite the absolute concentrations achieved, the ratio of FSH to LH and the ratio of oestradiol to oestrone did not change significantly on any of the hormone formulations used; and while FSH and LH were both suppressed to a significant degree on therapy neither was suppressed to premenopausal values suggesting the possibility of a 'female inhibin' in the normal regulation of gonadotrophin secretion.
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