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  • Title: Cushing's syndrome secondary to a neuroendocrine tumor: relapse after bilateral adrenalectomy.
    Author: Kitchens CS, Alexander RW.
    Journal: Cancer; 1981 Oct 15; 48(8):1873-6. PubMed ID: 6269728.
    Abstract:
    Bilateral adrenalectomy results in the removal of the site of glucocorticosteroid production thereby eliminating the signs and symptoms of Cushing's syndrome. A case is reported of a middle-aged man with Cushing's syndrome due to an ACTH-producing tumor. The patient initially responded to adrenalectomy but had a fatal relapse. Autopsy showed that the right adrenal bed containing remnants of adrenal tissue. An islet cell carcinoma of the pancreas was thought to be the primary tumor.
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