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  • Title: [Functional activity of mitochondria in experimental hypoparathyroidism].
    Author: Ovsepian RS, Ter-Markosian AS, Khudaverdian DN.
    Journal: Probl Endokrinol (Mosk); 1981; 27(5):75-9. PubMed ID: 6270650.
    Abstract:
    Respiration and oxidative phosphorylation of the brain and hepatic mitochondria, as well as the activity of succinate dehydrogenase, succinate-cytochrome-c-reductase and cytochrome oxydase were studied in experimental hypoparathyrosis. Activated respiration and decreased effectiveness of the brain and hepatic mitochondrial phosphorylation and enhanced succinate dehydrogenase activity are seen during hypoparathyrosis development. It is suggested that alterations in mitochondrial functional activity are caused not only by the changed blood calcium ion number, but also by hypoxia, developing in experimental hypoparathyrosis.
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