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  • Title: [Hairy cell leukemia. II.--Critical review of literature. Part. 1:diagnosis and evolution (author's transl)].
    Author: Bernadou A.
    Journal: Sem Hop; ; 57(33-36):1366-71. PubMed ID: 6270795.
    Abstract:
    Hairy cell leukemia (in french: leucémie à tricholeucocytes) is a distinctive form of chronic leukemia with splenomegaly, pancytopenia, presence of a particular circulating mononuclear cell, myelofibrosis and leukemia infiltration of the bone marrow. Generally, a tartrate resistant acid phosphatase activity is found in the leukemic cells. Hairy cell leukemia is the main leukemia in which the treatment is first surgical. Splenectomy has a good result for survival median and infectious risk. The disease is still mysterious for the origin of the leukemic cell; monocyte, B lymphocyte or in few cases T lymphocyte, even though a spectrum of immunological patterns pleads for the B lymphocyte origin of the leukemic cell.
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