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  • Title: [Liver tumours in pregnancy, following previous intake of hormonal contraceptives (author's transl)].
    Author: Pietsch P, Petermann J, Zipprich B, Schwesinger G, Kagel KO.
    Journal: Zentralbl Gynakol; 1981; 103(13):772-80. PubMed ID: 6270931.
    Abstract:
    Liver tumours developed in two women during pregnancy which followed discontinuation of hormonal contraception. Liver cell adenoma developed in a secundipara, 24 years of age, and its rupture during puerperium led to death by bleeding, after surgical intervention had failed. Hepatocellular carcinoma was recorded from a secundipara, 22 years of age, and surgically treated, following premature delivery. Problems of diagnosis and the need for interdisciplinary cooperation are discussed and compared with literature data. The pathogenesis of liver tumours in the wake of exogenous hormone inflow and in the context of subsequent pregnancy is another topic of discussion. Liver tumors developed in 2 women during pregnancy following discontinuation of hormonal contraception. Liver cell adenoma developed in a secundipara 24 years of age, and the rupture during pregnancy led to her death by bleeding after surgical intervention failed. Hepatocellular carcinoma was recorded in another secundipara 22 years of age and was surgically treated following a premature delivery. Problems of diagnosis and the need for interdisciplinary cooperation are discussed and compared with data appearing in the literature. The pathogenesis of liver tumors in the wake of exogenous hormone inflow and in the context of subsequent pregnancy are also discussed. (author's)
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