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Title: Furosemide and bumetanide-sensitive Na+ fluxes in erythrocytes from genetically hypertensive rats (SHR). Author: De Mendonca M, Grichois ML, Toumi K, Herubel A, Knorr A, Garay R, Meyer P. Journal: Clin Exp Hypertens (1978); 1981; 3(4):885-95. PubMed ID: 6271513. Abstract: Na+ and K+ fluxes from erythrocytes of SHR and WKY control rats have been studied. Fluxes were measured in both fresh and sodium-loaded (after exposure to ouabain or PCMBS) erythrocytes. Pump activity appears higher and furosemide or bumetanide sensitive Na+ efflux lower in SHR compared to WKY suggesting a similar abnormality in SHR genetic hypertension as in human hypertension.[Abstract] [Full Text] [Related] [New Search]