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  • Title: Reiterated sequences within the intron of an immediate-early gene of herpes simplex virus type 1.
    Author: Watson RJ, Umene K, Enquist LW.
    Journal: Nucleic Acids Res; 1981 Aug 25; 9(16):4189-99. PubMed ID: 6272198.
    Abstract:
    We describe the nucleotide sequence of a herpes simplex virus type 1 DNA fragment containing the intron of the immediate-early mRNA-5 (IE mRNA-5) gene. The location of the intron within this fragment was determined by a Berk & Sharp nuclease S1 protection analysis, and by cloning and sequencing cDNA containing sequences overlapping t he IE mRNA-5 splice point. We found that the 149 base pair (bp) intron contained four copies of an identical 23 bp GC rich tandem repeat followed by a further reiteration consisting of the first 15 bp only.
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