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  • Title: Eaton-Lambert myasthenic syndrome: long-term treatment of three patients with prednisone.
    Author: Streib EW, Rothner AD.
    Journal: Ann Neurol; 1981 Nov; 10(5):448-53. PubMed ID: 6272625.
    Abstract:
    Three patients with the myasthenic syndrome of Eaton-Lambert (ELS) were treated with prednisone for 6 and 12 months and more than 3 years, respectively. Muscle strength increased considerably in all, reaching a peak after 3 to 4 months, and was accompanied by simultaneous electromyographic improvement. Reduction of prednisone led to deterioration in all 3 patients; strength was regained when the higher dosage of prednisone was resumed. Prednisone is an alternative form of treatment for ELS, although the mechanism for its action is unclear.
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