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  • Title: [Cytochemical studies of peripheral blood granulocytes of workers with occupational exposure to lead compounds].
    Author: Hrycek A.
    Journal: Acta Haematol Pol; 1981; 12(1):23-7. PubMed ID: 6274122.
    Abstract:
    In 50 workers of a non-iron metallurgic plant exposed in their work to lead and trace amounts of cadmium and zinc cytochemical reactions were carried out in peripheral blood granulocytes. The control group comprised 30 men. In the investigations the degree of intoxication with lead compounds and the effect of the length of exposure ion the cytochemical reactions were taken into account. It was observed in these investigations that chronic exposure to lead and trace amounts of the remaining elements caused changes in the activity of acid phosphatase, alkaline phosphatase, lactic dehydrogenase and MOP. In particular, a significant fall of MOP and acid phosphatase activity and increased LDH activity in subjects exposed to lead with biochemical evidence of lead absorption deserve attention. With longer exposure to lead the activity of MPO decreased in workers with evidence of lead absorption.
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