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  • Title: An open, multi-centre evaluation of a 5-day course of pivmecillinam in urinary tract infections in general practice.
    Author: Place C.
    Journal: Pharmatherapeutica; 1981; 3(1):55-60. PubMed ID: 6275417.
    Abstract:
    One hundred and eleven general practice patients (101 females and 10 males) with acute uncomplicated cystitis received a 5-day course of pivmecillinam at a daily dose of 200 mg 3-times a day. Positive bacteriological cultures were found in 63 (57%) patients before treatment and three-quarters of all patients were totally symptom-free after treatment, with the post-treatment clinical symptom score falling by 94%. In those patients with a positive culture the bacteriological cure rate was 90%. Pivmecillinam was generally well tolerated. Side-effects were reported in 8 (7%) patients and only 1 of these patients had to stop treatment prematurely.
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