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  • Title: [Genome instability and neoplasia].
    Author: Shapot VS, Mironov NM.
    Journal: Tsitol Genet; 1981; 15(6):73-83. PubMed ID: 6275583.
    Abstract:
    Necessity of oncogene for the neoplastic cell transformation is substantiated. The oncogene may be introduced into the cell by a virus; be present in the cell from its formation but be repressed by products of regulatory genes; be arisen from separated DNA segments. The latter possibility is discussed in view of data on the presence of mobile elements and Sarc sequences in the cell genome.
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