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  • Title: Effect of colostral antibody on bovine leukemia virus infection of neonatal calves.
    Author: Van Der Maaten MJ, Miller JM, Schmerr MJ.
    Journal: Am J Vet Res; 1981 Sep; 42(9):1498-500. PubMed ID: 6275754.
    Abstract:
    Pairs of newborn calves were exposed to bovine leukemia virus (BLV) when they were given their 1st colostrum feeding. Calves that were given 10(6) BLV-infected lymphocytes in colostrum free of BLV-specific antibody became infected. Calves that were fed 10(7), 10(8), or 10(9) infected lymphocytes in colostrum that contained BLV-specific antibody did not become infected. One of 2 calves inoculated intradermally with 250,000 infected lymphocytes was protected by colostral antibody, but the other was not. Colostral antibody titers in the unprotected calf decreased normally until the calf was 4 months old and then increased markedly; this pattern indicates that the presence of colostral antibody may have prolonged the latent period of the BLV infection.
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