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  • Title: Nucleotide sequence of cloned cDNA encoding bovine arginine vasopressin-neurophysin II precursor.
    Author: Land H, Schütz G, Schmale H, Richter D.
    Journal: Nature; 1982 Jan 28; 295(5847):299-303. PubMed ID: 6276766.
    Abstract:
    The sequence of a cDNA encoding the nonapeptide arginine vasopressin (AVP) and its carrier protein, neurophysin II (NpII) from bovine hypothalamus, proves that the 166-amino acid precursor molecule contains a signal peptide of 19 amino acids followed directly by AVP connected to NpII by a Gly-Lys-Arg sequence. The carboxy-terminal region of the precursor contains a naturally occurring glycopolypeptide of 39 amino acids which is separated from NpII by a single arginine residue.
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