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  • Title: [Carcinoembryonic antigen in serum and tissue of benign and cancerous breast lesions].
    Author: von Kleist S, Wittekind C, Polack M, Gropp H, Sandritter W.
    Journal: Arch Geschwulstforsch; 1981; 51(6):523-6. PubMed ID: 6277268.
    Abstract:
    The tissular CEA was studied with the immunoperoxidase method and the circulating CEA with the enzyme immunoassay (EIA), using peroxidase-coupled antibodies. 51 cases of mammary cancers as well as 33 benign lesions were examined in order to study a possible correlation between the frequency of CEA-positive tissues and CEA-positive sera in the same patient. It has been confirmed that CEA-positive tumors can be accompanied by low or negative CEA serum levels. An attempt was made to analyze the stage and the histologic type of lesions in comparison to the positivity and the increase of CEA.
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