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  • Title: [Channel formation properties of black widow venom].
    Author: Krasil'nikov OV, Ternovskiĭ VI, Tashmukhamedov BA.
    Journal: Biofizika; 1982; 27(1):72-5. PubMed ID: 6279171.
    Abstract:
    Black widow venom in the concentration 1--10 mkg/ml added on one side of the bilayer of common bovine brain phospholipids induces the formation of conductivity channels with high cation-anion selectivity with the number of cation transfer for K+, Ca2+, Sr2+, Mg2+, Na+, Cs+, Li+ equaling 0.98, 0.97, 0.96, 0.94. 0.88. 0.82, 0.82 correspondingly (at pH = 7.5). At pH less than 3.5 the channels are slightly selective for anions (the number of cation transfer 0.4). Potential-dependence of the channels is found, which is explained by microstructural reconstruction of their protein complex.
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