These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Calcium: calmodulin and cancer.
    Author: Criss WE, Kakiuchi S.
    Journal: Fed Proc; 1982 May; 41(7):2289-91. PubMed ID: 6281083.
    Abstract:
    When several fast-growing Morris hepatoma tissue lines are compared with normal adult liver tissue, the following observations are made: calmodulin activity is increased in the cytoplasm and decreased in the membrane of the tumor cells. Total calcium is increased three- to fivefold in the tumors. Cyclic AMP phosphodiesterase activity is increased, whereas cyclic GMP phosphodiesterase activity is decreased. In addition, several of the fast-growing Morris hepatoma tissue lines have a new calcium-binding protein that is not observed in adult liver tissue. It is probable that the Ca2+-calmodulin complex is very active in these rapidly growing tumors.
    [Abstract] [Full Text] [Related] [New Search]