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  • Title: Spin label electron paramagnetic resonance (EPR) studies of Huntington disease erythrocyte membranes.
    Author: Fung LW, Ostrowski MS.
    Journal: Am J Hum Genet; 1982 May; 34(3):469-80. PubMed ID: 6282120.
    Abstract:
    Several spin-label electron paramagnetic resonance (EPR) studies of red cell membranes appear to show abnormalities in some Huntington disease (HD) patients, but not in others. Both studies measure the W/S ratios, presumably under similar conditions, but have different results. We have studied the W/S ratio in some detail to gain a better understanding of this experimental parameter and to determine its potential application in detecting HD abnormalities. Our results offer little encouragement for continued use of W/S as an indication of membrane defect in HD.
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