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Title: Osmotic swelling of phospholipid vesicles causes them to fuse with a planar phospholipid bilayer membrane. Author: Cohen FS, Akabas MH, Finkelstein A. Journal: Science; 1982 Jul 30; 217(4558):458-60. PubMed ID: 6283637. Abstract: Fusion of phospholipid vesicles with planar bilayer membranes occurs if the vesicles that contact the planar membrane swell osmotically after the replacement in their medium of an impermeant solute by a permeant one. This finding directly demonstrates that osmotic swelling is a driving force for vesicle-planar membrane fusion. The method used to induce vesicle swelling and fusion may have relevance for biological systems.[Abstract] [Full Text] [Related] [New Search]