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  • Title: The bone scan as a tumour marker in prostatic carcinoma.
    Author: Chisholm GD, Stone AR, Beynon LL, Merrick MV.
    Journal: Eur Urol; 1982; 8(5):257-60. PubMed ID: 6288389.
    Abstract:
    The technetium methylene diphosphate bone scan was elevated in 100 consecutive new patients presenting with carcinoma of the prostate. 48% of the patients has a positive bone scan at the initial diagnosis. The scan was more helpful than the skeletal X-ray in the diagnosis of bone metastases: 23% of the X-ray-negative patients were scan-positive. Serial bone scans were more sensitive than either X-rays or serum acid phosphatase in following the progress of the disease. It is concluded that the bone scan in patients with prostatic carcinoma can be used as a reliable tumour marker, especially for monitoring the course of metastases.
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