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  • Title: Resistance to prolonged irradiation in mice influenced by thyroid hormones and chemical radiation protectors.
    Author: Hosek B, Misustová J, Lojek A, Kautská J.
    Journal: Acta Radiol Oncol; 1982; 21(2):115-20. PubMed ID: 6289611.
    Abstract:
    After the end of 10 and 21 days' treatment of mice with dried thyroid gland (0.6 g/100 g diet) the effect of some radiation protectors against prolonged irradiation (38 mGy/min) increased. The combination of propranolol, phenobarbital and cystamine was more effective than a mixture of cystamine and 5-methoxytryptamine both in mice fed on a normal and a thyroid gland diet. A reduced oxygen consumption after the application of protectors reflected the degree of protection. The number of thrombocytes in peripheral blood increased after the end of thyroid treatment, which indicated a possible shift in the differentiation of stem cells in favour of megakaryocytes.
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