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  • Title: [11-hydroxycorticosteriod content in the peripheral blood plasma and in the cerebrospinal fluid in acute disorders of the cerebral circulation].
    Author: Lebedev ED.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1978; 78(1):66-72. PubMed ID: 629146.
    Abstract:
    The author studied the glucocorticoid function of the adrenal cortex in 93 patients (40 males and 53 females) with acute disturbances of brain circulation, in 59 patients with ischemic strokes and 21 patients with cerebral hemorrhages. The functional activity of the adrenal cortex was judged by the content of 11-oxycorticosteroids in the plasma of the peripheral blood and in the liquor in the dynamics during 4 weeks from the beginning of the stroke. The patients with a severe course of the stroke (in spite of its character) demonstrated a statistically significant increase of 11-OCS concentration in the above-mentioned biological fluids during the acute period of the disease (first 14 days).
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