These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Detergent effects of kinetic properties of (Na+ +K+)-ATPase from kidney membranes.
    Author: Foussard-Guilbert F, Ermias A, Laget P, Tanguy G, Girault M, Jallet P.
    Journal: Biochim Biophys Acta; 1982 Nov 08; 692(2):296-304. PubMed ID: 6293563.
    Abstract:
    Studies on (Na+ +K+)-ATPase generally employ detergents such as SDS and deoxycholate. Under such conditions, the purified enzyme possesses high specific activity. The (Na+ +K+)-ATPase from kidney membranes was unmasked by deoxycholate and SDS as described by Jłrgensen and its kinetic properties were studied. The results suggest that these detergents induce some irreversible alterations in the kinetic properties of the native enzyme. Another detergent, saponin, unmasked the (Na+ +K+)-ATPase as effectively as did SDS, but it seems to affect the kinetic properties of the native enzyme to a lesser extent.
    [Abstract] [Full Text] [Related] [New Search]