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  • Title: [Study of thesaurismosis induced by perhexiline maleate. Confirmation of experimental data].
    Author: Turpin JC, Pluot M, Albouz S, Bajolet A, Caulet T, Baumann N.
    Journal: Sem Hop; 1983 Jan 06; 59(1):58-61. PubMed ID: 6297091.
    Abstract:
    Perhexiline maleate is an amphiphilic molecule. Along with many other drugs it is responsible for experimental and, in some instances, clinical lipidoses. Sphingomyelinase deficiency has been evidenced in cell cultures incubated with perhexiline maleate. We describe the occurrence of a similar defect in a patient. The disturbances in the phospholipid turnover which are responsible for the thesaurismosis may originate in the sphingomyelinase deficiency.
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