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  • Title: Synergism among BIOLF-62, phosphonoformate, and other antiherpetic compounds.
    Author: Smith KO, Galloway KS, Ogilvie KK, Cheriyan UO.
    Journal: Antimicrob Agents Chemother; 1982 Dec; 22(6):1026-30. PubMed ID: 6297382.
    Abstract:
    9-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine (BIOLF-62) is highly synergistic with either phosphonoformate or phosphonoacetate when used in combination against herpes simplex virus types 1 and 2 in vitro. Acycloguanosine did not show significant synergism with these two compounds. Bromovinyldeoxyuridine and phosphonoformate were highly synergistic against herpes simplex virus type 2, but not against type 1.
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