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  • Title: [Evaluation of the treatment of symptomatic urinary tract infection with a single dose of antibiotics or bicarbonate].
    Author: Darioli R, Chappuis P, Dubi J.
    Journal: Schweiz Med Wochenschr; 1983 Jan 08; 113(1):14-6. PubMed ID: 6298934.
    Abstract:
    68 women with acute, uncomplicated urinary tract infection confirmed bacteriologically were randomized to receive either a single oral dose of cotrimoxazole, a single oral dose of amoxycillin, or an oral dose of Na-bicarbonate. Results comparable to previous reports were obtained with the cotrimoxazole regimen. On the other hand, the efficacy of single-dose amoxycillin appeared to be inferior. It is possible that pharmacocinetic differences influence the efficacy of these drugs.
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