These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The influence of sulfide and cyanide on axonal function.
    Author: Beck JF, Donini JC, Maneckjee A.
    Journal: Toxicology; 1983 Jan; 26(1):37-45. PubMed ID: 6298976.
    Abstract:
    The absorption of hydrogen sulfide (H2S) gas by sciatic nerve bundles from Rana pipiens produces an anaesthetic effect of short duration. Subsequent compound action potential (CAP) levels are higher than before exposure while the conduction velocity (CV) shows only small variation. Exposure to hydrogen cyanide (HCN) gas produces declining CAP and CV levels. The effect of H2S on the CAP is faster than that of HCN and the recovery time is shorter, although there is evidence of permanent change. Unlike HCN there is no indication that H2S inhibits the energy metabolism of the nerve cells, except possibly when the nerves are exposed to extremely high sulfide concentrations. A mode of action for H2S is proposed.
    [Abstract] [Full Text] [Related] [New Search]