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  • Title: Evaluation of a killed feline panleukopenia virus vaccine against canine parvoviral enteritis in dogs.
    Author: Wierup M, Olson P, Hedhammar A, Klingeborn B, Karlsson KA.
    Journal: Am J Vet Res; 1982 Dec; 43(12):2183-7. PubMed ID: 6299140.
    Abstract:
    Immunogenic potency of a killed feline panleukopenia virus vaccine against canine parvoviral enteritis in dogs was examined. The vaccine elicited hemagglutination-inhibition antibodies to canine parvovirus (CPV) in all of the 72 dogs which were vaccinated. The vaccine was protective in dogs against both experimentally induced and naturally occurring CPV-induced disease. By statistical analysis, 4 weeks was found to be the optimal spacing between 2 vaccinal doses resulting in hemagglutination-inhibition antibody titers up to 1:5,120. Adverse reactions to the vaccine were not observed. Atypical lymphocytes were found consistently in the CPV-infected control dogs.
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