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  • Title: The presence of phospholipase D in rat central nervous system axolemma.
    Author: DeVries GH, Chalifour RJ, Kanfer JN.
    Journal: J Neurochem; 1983 Apr; 40(4):1189-91. PubMed ID: 6300326.
    Abstract:
    An axolemma-enriched fraction prepared from a purified myelinated axon fraction isolated from rat CNS was found to contain phospholipase D at a specific activity similar to that of a microsomal fraction isolated from whole brain. There was a concomitant threefold enrichment in the specific activity of phospholipase D and acetylcholinesterase in the axolemma-enriched fraction compared with the specific activities of these enzymes in the starting white matter whole homogenate. This axonal phospholipase D may be involved in remodeling of phospholipid, which in turn may affect axonal functions such as ion translocation.
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